AM to PM:
Anti-Aging Routine
30-day supply • HSA|FSA-eligible
One simple routine that targets signs of aging around the clock.
These two custom prescription formulas work together to target your skin goals for 24/7 treatment.
DayPrimeᴿˣ: Get soft-focus, smoother-looking skin and help treat acne with personalized, prescription active ingredients in this 2-in-1 daytime acne treatment and primer.
HydroTretᴿˣ: Help boost hydration and prevent the earliest signs of aging with tretinoin formula—designed to be our most hydrating personalized formula.
Made to treat:
*Subscription required. Subject to medical consultation. New subscribers only. Restrictions apply.
Save $30 on all future shipments when you pair AM/PM treatments
Results you can see and feel
Mu
I am satisfied with my journey.
Courtney
My skin is nearly perfect thanks to Curology!
Vivian
It changed my skin.
Trevor
My skin has gotten much clearer and smoother.
Melissa
I saw results in the first 2 weeks and was hooked from there. Not sure I’ll ever be without my Curology products.
Annie
It helps with my acne, and it helps with the dryness that tretinoin typically causes.
Marian
It has improved my skin drastically and helped get rid of the painful cysts I used to get.
Emily
Things are starting to clear up!
Audra
[I] switched to the HydroTretᴿˣ, and now that has been working great for me!
Sheri
My skin became smoother with a noticeable glow that made my skin look less tired.
The power duo for clearer skin
First thing in the morning: DayPrimeᴿˣ
Prepare your skin for the day ahead with the first-ever prescription acne treatment and blurring primer in one. A soft-focus finish today, clearer-looking skin in the days ahead.
Last thing at night: HydroTretᴿˣ
Apply your personalized treatment after cleansing at night and let the custom combination of active ingredients go to work while you sleep.
First thing in the morning: DayPrimeᴿˣ
Prepare your skin for the day ahead with the first-ever prescription acne treatment and blurring primer in one. A soft-focus finish today, clearer-looking skin in the days ahead.
Last thing at night: HydroTretᴿˣ
Apply your personalized treatment after cleansing at night and let the custom combination of active ingredients go to work while you sleep.
First thing in the morning: DayPrimeᴿˣ
Prepare your skin for the day ahead with the first-ever prescription acne treatment and blurring primer in one. A soft-focus finish today, clearer-looking skin in the days ahead.
Last thing at night: HydroTretᴿˣ
Apply your personalized treatment after cleansing at night and let the custom combination of active ingredients go to work while you sleep.
First thing in the morning: DayPrimeᴿˣ
Prepare your skin for the day ahead with the first-ever prescription acne treatment and blurring primer in one. A soft-focus finish today, clearer-looking skin in the days ahead.
Last thing at night: HydroTretᴿˣ
Apply your personalized treatment after cleansing at night and let the custom combination of active ingredients go to work while you sleep.
First thing in the morning: DayPrimeᴿˣ
Prepare your skin for the day ahead with the first-ever prescription acne treatment and blurring primer in one. A soft-focus finish today, clearer-looking skin in the days ahead.
Treat and prime at the same time
DayPrimeᴿˣ locks in a day’s worth of treatment while smoothing your skin for whatever comes next.
Helps treat acne
Visibly blurs imperfections
Evens out texture
Minimizes the look of pores
Smooth, long-lasting results
HydroTretᴿˣ is designed to work over time, with active ingredients that can help:
Boost natural collagen production
Fade dark spots
Attract and hold moisture for smoother, softer skin
Proven ingredients, personalized formulas
Helps clear acne and smooth out texture and fine lines
- Acne
- Fine lines
- Dark spots
- Texture
Gently exfoliates to help unclog pores, smooth texture, and brighten skin
- Clogged pores
- Dark spots
- Redness
- Texture
Fights acne-contributing bacteria and soothes inflammation
- Acne
- Clogged pores
- Inflammation
Soothes inflammation, helps visibly fade dark spots, and fights free radicals
- Acne
- Dark spots
- Inflammation
Soothes inflammation and acts against both bacteria and fungus that contribute to acne
- Acne
- Clogged pores
- Inflammation
Goes deep into pores to clear away dead skin cells and excess oil
- Acne
- Clogged pores
Attracts and holds moisture for softer, smoother skin
- Hydration
- Texture
Personalized to target your skin goals
Formulated for you
Active ingredients hand-picked for your skin
Science-backed for proven results
Dermatologist-tested and clinically studied for measurable results you can see and feel
Expert input at every step
Your provider is always available to answer questions and provide ongoing support
Formulated for you
Active ingredients hand-picked for your skin
Science-backed for proven results
Dermatologist-tested and clinically studied for measurable results you can see and feel
Expert input at every step
Your provider is always available to answer questions and provide ongoing support
Formulated for you
Active ingredients hand-picked for your skin
Science-backed for proven results
Dermatologist-tested and clinically studied for measurable results you can see and feel
Formulated for you
Active ingredients hand-picked for your skin
Science-backed for proven results
Dermatologist-tested and clinically studied for measurable results you can see and feel
Formulated for you
Active ingredients hand-picked for your skin
FAQs
A licensed dermatology provider selects 3 active ingredients at the right strength for your skin.
Potential active ingredients include:
Azelaic acid: A multitasking exfoliant that helps unclog pores, smooth texture, and brighten skin
Clindamycin phosphate: An antibiotic that fights acne-contributing bacteria and soothes inflammation
Niacinamide: A form of vitamin B3 that soothes inflammation, helps visibly fade dark spots, and fights free radicals
Zinc pyrithione: An antimicrobial that helps keep bacteria and fungi in check while soothing inflammation
Salicylic acid: A chemical exfoliant that clears away dead skin cells, dirt, and excess oil
Dexpanthenol: A vitamin B5 derivative that attracts and holds moisture for softer, smoother skin
Inactive ingredients: 1,2-hexanediol, butylene glycol, caprylyl glycol, ceramide NP, cetearyl olivate, dimethicone, glycerin, hydroxyacetophenone, oryza sativa (rice) starch, polyacrylate crosspolymer-6, polyhydroxystearic acid, polymethyl methacrylate, polymethylsilsesquioxane, polysorbate 20, PVP, sorbitan olivate, trisodium ethylenediamine disuccinate, water (aqua)
Formulas containing dexpanthenol also contain propylene glycol.
A licensed dermatology provider selects 3 active ingredients at the right strength for your skin. Potential active ingredients include:
Tretinoin: A prescription retinoid that helps smooth texture and fine lines while brightening skin by speeding up cell turnover and boosting collagen production
Dexpanthenol (aka provitamin B5): A vitamin B5 derivative that attracts and holds moisture for softer, smoother skin
Niacinamide: A form of vitamin B3 that fights free radicals, helps visibly fade dark spots, and improves moisture barrier function
Azelaic acid: A gentle exfoliant that clears away dull, dead skin cells and reduces excess pigment to help smooth texture and brighten skin
Inactive ingredients: Aloe Barbadensis Leaf Juice, C13-C14 Isoparaffin, Caprylic/Capric Triglyceride, Deionized Water, Laureth-7, Phenoxyethanol, Polyacrylamide, Tocopheryl Acetate, Triethylene Glycol All formulas containing tretinoin also contain the antioxidant butylated hydroxytoluene (BHT), and formulas containing both niacinamide and azelaic acid may also contain propylene glycol. All formulas containing dexpanthenol also contain propylene glycol.
In the AM: Apply a thin layer of DayPrimeᴿˣ to clean, dry skin and allow it to dry fully before adding makeup or sunscreen. Your personalized prescription will go to work targeting your long-term goals while keeping your skin smooth and ready for whatever comes next.
In the PM: Apply a thin layer of HydroTretᴿˣ after cleansing and allow to dry fully before moisturizing. Your personalized prescription will go to work while you sleep.
Since these are prescription products, always follow your licensed dermatology provider’s instructions for how to best use them with your unique skin.
Your Curology dermatology provider will prescribe your formulas containing 3 active ingredients based on your skin quiz, photos, and medical history. Your formulas will target your specific skin concerns and can evolve with you over time!
With consistent use, many patients using these types of ingredients notice a difference with their acne within 6-12 weeks—but everyone’s skin is different, so this timeline might vary for you. It’s also important to remember that this is a long-term journey! We’re not just going for progress, but also prevention.
You may be able to use your HSA or FSA pre-tax dollars for this Curology product, plus some of our other acne treatments and sunscreens. Check with your plan’s administrator to confirm eligibility. Restrictions apply.
After your 30-day free trial, you can update your payment method to your HSA or FSA card via your account dashboard. Or you can use a credit or debit card and submit a claim for reimbursement—just download your itemized receipt for your order from your account dashboard.
