How it works:
Share your skin goals and snap selfies
Your dermatology provider prescribes your formula
Apply nightly for happy, healthy skin
How it works:
How it works:
Share your skin goals and snap selfies
Your dermatology provider prescribes your formula
Apply nightly for happy, healthy skin
How it works:


Your morning skincare routine should do more than just make you look good; it should help you make long-term improvements to your skin. DayPrime Rx is the first prescription acne treatment and blurring primer that works on two timelines: instant visual improvement through a soft-focus blurring effect, and improving skin concerns over time through clinically proven prescription actives. Unlike traditional primers that simply mask imperfections, DayPrime Rx combines personalized prescription ingredients (like azelaic acid, niacinamide, salicylic acid, and more) with a primer base that visibly blurs imperfections and minimizes the look of pores. It's the foundation of a science-backed morning routine that treats and blurs, helping you build confidence that comes from knowing your skin concerns are being addressed with clinically proven active ingredients, not just covered up.
DayPrime Rx offers clinically proven active ingredients in combination with a blurring primer base, along with personalization and care from licensed dermatology providers that you can’t get off the shelf. DayPrime Rx was designed to offer:
Instant Visual Refinement: The primer base minimizes the appearance of pores and creates a soft-matte finish for seamless makeup application.
Long-Term Transformation: While you go about your day, prescription actives penetrate the skin. For example, azelaic acid gently exfoliates to help unclog pores, smooth texture, and brighten skin, while clindamycin combats acne-contributing bacteria.
Building an effective morning routine isn't just about having the right products; it's about using them in the right order to maximize their benefits. Here's how DayPrime Rx can be integrated seamlessly into an AM ritual:
Step 1: Cleanse. Start with a gentle cleanser to remove overnight oil buildup and create a fresh canvas. You don't need anything harsh or stripping, just a reset that leaves your skin feeling clean and balanced.
Step 2: Moisturize. Yes, even before DayPrime Rx. Hydrated skin is happy skin, and moisturizer helps ensure your skin barrier is supported before you apply active ingredients.
Step 3: Apply DayPrime Rx. Here's where the magic happens. Use as directed by your licensed dermatology provider and gently pat, don't rub, it into your skin. Rubbing may cause pilling or uneven application. Let it dry fully before moving to the next step. This usually takes about a minute. Since this is a prescription product, always follow your Licensed Dermatology Provider’s instructions for how to best use it with your unique skin.
Step 4: Sunscreen. Non-negotiable. Always. Certain prescription actives can make your skin more sensitive to UV damage, and sun protection is essential for helping prevent dark spots and premature aging. Sunscreen with broad-spectrum SPF 30+ is a crucial step in every morning routine.
Step 5: Makeup (optional). If you wear foundation or concealer, DayPrime Rx is designed to help them glide on more smoothly and last longer. For best results, pair with silicone-based foundations.
This routine typically takes less than five minutes but is designed to deliver all-day benefits. You're protecting your skin from environmental damage, actively treating your concerns with prescription ingredients, and creating a smooth base for whatever the day throws at you.
Let's talk about what "blurring" actually means in skincare, because it's not just a buzzword, it's optical science.
Traditional blurring relies heavily on light-diffusing particles that scatter light away from textural irregularities, making pores and fine lines less visible. Think of it like Instagram's blur filter but in cream form. It's effective for photos and short-term appearance, but it doesn't address the underlying texture.
DayPrime Rx uses a more sophisticated approach. Yes, it visibly blurs to soften the appearance of imperfections. But it also contains ingredients that work over time to actually address your skin goals, such as helping reduce excess oil and unclogging the pores. When your pores are less clogged, they may appear smaller.
The same principle applies to texture. Smoothing agents in the formula create immediate visible surface refinement, while exfoliating actives like salicylic acid work progressively to slough off dead skin cells and reveal smoother skin beneath. You get the instant gratification of looking better today and the long-term satisfaction of genuine skin improvement.
If you have oily skin, you know the mid-day struggle. Your makeup slides off. Your T-zone turns into an oil slick. You're constantly reaching for blotting papers or powder. It's exhausting.
DayPrime Rx was designed with oily skin in mind, and here's how it can help: instead of just absorbing surface oil (which is what mattifying primers and powders are designed to do), it can address oil production at the source.
Niacinamide and azelaic acid, both commonly prescribed in DayPrime Rx formulas, help regulate sebum production, helping to control excess oil. Salicylic acid helps keep pores clear of the oil and debris that can make them appear larger and more visible.
The result? You're not just managing shine, you're helping prevent it. Your skin stays balanced, your makeup stays in place, and you spend less time worrying about whether you look greasy.
Texture issues, whether it's enlarged pores, rough patches, or uneven tone, can make even the best makeup application look less than flawless. You can use all the primers and foundations in the world, but if your skin's surface isn't smooth, nothing sits quite right.
This is where exfoliating ingredients shine. Salicylic acid works inside the pore to clear out congestion, which over time leads to visibly refined pores. Azelaic acid gently exfoliates to help improve skin texture.
The blurring effect of the DayPrime Rx primer base gives you immediate visible texture smoothing, while the actives work progressively to improve your skin's actual texture. It's not just about looking smooth for a few hours; it's about waking up in a few weeks and noticing that your skin genuinely feels and looks smoother, even before you apply anything.
Post-inflammatory hyperpigmentation (PIH), those dark marks left behind after acne heals, can linger for months. And while nighttime treatments can certainly help, why limit your progress to just eight hours?
If dark spots are a concern, your dermatology provider might prescribe DayPrime Rx with azelaic acid, which gently exfoliates and lightens dark spots over time. Unlike some brightening ingredients that can only be used at night due to sun sensitivity, azelaic acid can be used during the daytime when paired with sunscreen.
This means your skin is actively working to fade dark spots throughout the day while you're at work, running errands, or hanging out with friends. You're not just covering up discoloration with concealer, you're treating it for long-term improvements.
DayPrime Rx is designed for daytime use on its own, or it can be paired with a nighttime treatment such as Custom Formula Rx or HydroTret Rx. This is the concept of around-the-clock skincare: maximizing the benefits of prescription ingredients by treating your skin 24/7.
During the day, DayPrime Rx focuses on visibly blurring imperfections, targeting your skin concerns, and priming the skin for the day.
At night, you can incorporate other actives like topical retinoids such as tretinoin (offered in Custom Formula Rx or HydroTret Rx) that support cell turnover, boost collagen production, and address signs of aging. Your skin is in repair mode while you sleep, making nighttime the ideal window for intensive treatment.
Using complementary day and night prescriptions means you're attacking your skin concerns from multiple angles with clinically proven, multitasking ingredients. It's not about overloading your skin; it's about strategic, clinically-informed treatment that is designed to maximize efficacy.
No two skin stories are the same, which is why your formula is personalized based on factors such as your skin goals, photos, and medical history. A licensed dermatology provider selects ingredients based on your specific concerns and goals—whether that’s salicylic acid for clogged pores or azelaic acid for fading dark spots. This isn't a one-size-fits-all product; it can be adjusted in partnership with your dermatology provider as your skin evolves and as your goals change.
We live in a world of instant gratification, and the beauty industry has capitalized on that by promising immediate transformations. But here's the truth: real skin change takes time.
DayPrime Rx is transparent about this. You'll see instant temporary visual improvements from the blurring and smoothing effects of the primer base, yes. But the prescription ingredients? They need time to work.
The difference is that, unlike those miracle creams promising overnight results, DayPrime Rx is actually doing something beneath the surface. Every single day you use it, prescription actives are penetrating your skin, regulating oil production, unclogging pores, fighting bacteria, fading hyperpigmentation, and supporting a healthier skin barrier.
You might not notice dramatic changes day-to-day, but take a photo today and compare it to one in six weeks. You’ll start to notice the progress. Real, measurable improvement that doesn't wash off when you cleanse your face.
Rx products are subject to medical consultation. Results may vary. Restrictions apply.
Can I use DayPrime Rx if I don't wear makeup? Absolutely. DayPrime Rx provides a naturally refined, soft-focus finish that many users prefer on “no-makeup days”, as well as a first step for a makeup routine.
How long does it take to see results from DayPrime Rx? You'll notice instant visual improvements (blurred appearance of pores, smoother-looking texture) upon application. However, the clinical benefits from the prescription ingredients take longer to manifest. Many patients using these types of ingredients notice a difference with their acne within 6-12 weeks, but everyone’s skin is different, so this timeline might vary for you. It’s also important to remember that this is a long-term journey! We’re not just going for progress, but also prevention. For best results, use DayPrime Rx every morning and consider pairing with a nighttime prescription treatment for around-the-clock care.
Will DayPrime Rx make my skin oily or cause breakouts? DayPrime Rx is specifically formulated to help control oil and prevent breakouts, not cause them. The prescription ingredients offered in DayPrime Rx (such as niacinamide, salicylic acid, and azelaic acid) can help control excess oil and keep pores clear. However, as with any new skincare product, there may be an adjustment period. If you experience initial purging (temporary breakouts as your skin clears out congested pores), know that this is temporary! If this happens, reach out to your licensed dermatology provider for further guidance.
What's the difference between DayPrime Rx and regular drugstore primers? The fundamental difference is that DayPrime Rx is a prescription treatment with clinically proven active ingredients prescribed by a licensed dermatology provider, while drugstore primers are typically cosmetic products with no therapeutic benefit.

Curology Team

Elise Bradley, PA-C



