AM to PM: Acne Routine
30-day supply • HSA|FSA-eligible
One simple routine that treats acne around the clock.
These two custom prescription formulas work together to target your skin goals for 24/7 treatment.
DayPrimeᴿˣ: Get soft-focus, smoother-looking skin and help treat acne with personalized, prescription active ingredients in this 2-in-1 daytime acne treatment and primer.
Custom Formulaᴿˣ: Help clear your skin with a personalized, prescription acne treatment made with 3 clinically proven ingredients selected to target your skin goals.
Made to treat:
*Subscription required. Subject to medical consultation. New subscribers only. Restrictions apply.
Save $30 on all future shipments when you pair AM/PM treatments








Results you can see and feel




Mista
It takes patience, but with Curology [it’s] worth it.




Lauren
Not only did Curology help with my acne, but my skin has been glowing too! I feel so much happier, confident, and myself!




Alejandro
I love Curology. Their products have changed my life.




Aaliyah
I’m so glad I gave Curology a chance! I’m in love with my results!




Stina
Within a month Curology has calmed my acne—I’m hooked!




Jennifer
I started using Curology and never looked back. I could see it was working within the first month of using my Custom Formulaᴿˣ.




Jeanne
I honestly love Curology. It is the only sure thing for my skin.




Avalon
I hear constantly, ‘Your face looks so nice!’ I reply, ‘Thanks to Curology!’




Mark
I decided I was just going to see it through. Progress pictures definitely helped me stay consistent.




Anjelica
There is such a huge difference from when I started. I am so happy with how my face looks now!
The power duo for clearer skin

First thing in the morning: DayPrimeᴿˣ
Prepare your skin for the day ahead with the first-ever prescription acne treatment and blurring primer in one. A soft-focus finish today, clearer-looking skin in the days ahead.

Last thing at night: Custom Formulaᴿˣ
Apply your personalized treatment after cleansing at night and let the custom combination of active ingredients go to work while you sleep.
Treat and prime at the same time
Get smoother-looking skin and help treat acne at the same time.
Prescription active ingredients
Visibly blurs imperfections
Evens out texture
Minimizes the look of pores

Custom-made for clearer skin
90.5%* of users report an improvement in acne at 3 just weeks using Custom Formulaᴿˣ
Targets acne, rosacea, dark spots, texture, and more
Reduces oiliness
Made using active ingredients selected for you

Proven ingredients, personalized formulas

Helps clear acne and smooth out texture and fine lines
- Acne
- Fine lines
- Dark spots
- Texture

Gently exfoliates to help unclog pores, smooth texture, and brighten skin
- Clogged pores
- Dark spots
- Redness
- Texture

Fights acne-contributing bacteria and soothes inflammation
- Acne
- Clogged pores
- Inflammation

Soothes inflammation, helps visibly fade dark spots, and fights free radicals
- Acne
- Dark spots
- Inflammation

Soothes inflammation and acts against both bacteria and fungus that contribute to acne
- Acne
- Clogged pores
- Inflammation

Helps lighten dark spots and reduce redness

Goes deep into pores to clear away dead skin cells and excess oil
- Acne
- Clogged pores

Attracts and holds moisture for softer, smoother skin
- Hydration
- Texture
Personalized to target your skin goals

Formulated for you
Active ingredients hand-picked for your skin

Science-backed for proven results
Dermatologist-tested and clinically studied for measurable results you can see and feel

Expert input at every step
Your provider is always available to answer questions and provide ongoing support
FAQs
A licensed dermatology provider selects 3 active ingredients at the right strength for your skin.
Potential active ingredients include:
Azelaic acid: A multitasking exfoliant that helps unclog pores, smooth texture, and brighten skin
Clindamycin phosphate: An antibiotic that fights acne-contributing bacteria and soothes inflammation
Niacinamide: A form of vitamin B3 that soothes inflammation, helps visibly fade dark spots, and fights free radicals
Zinc pyrithione: An antimicrobial that helps keep bacteria and fungi in check while soothing inflammation
Salicylic acid: A chemical exfoliant that clears away dead skin cells, dirt, and excess oil
Dexpanthenol: A vitamin B5 derivative that attracts and holds moisture for softer, smoother skin
Inactive ingredients: 1,2-hexanediol, butylene glycol, caprylyl glycol, ceramide NP, cetearyl olivate, dimethicone, glycerin, hydroxyacetophenone, oryza sativa (rice) starch, polyacrylate crosspolymer-6, polyhydroxystearic acid, polymethyl methacrylate, polymethylsilsesquioxane, polysorbate 20, PVP, sorbitan olivate, trisodium ethylenediamine disuccinate, water (aqua)
Formulas containing dexpanthenol also contain propylene glycol.
A licensed dermatology provider selects 3 active ingredients at the right strength for your skin.
Potential active ingredients include:
Tretinoin: A prescription topical retinoid that helps clear acne and smooth out texture and can improve dark spots and fine lines
Spironolactone: A medication that helps stop the cycle of persistent hormonal acne by reducing the skin’s oil production
Azelaic acid: A multitasking exfoliant that helps unclog pores, smooth texture, and brighten skin
Niacinamide: A form of vitamin B3 that soothes inflammation, helps visibly fade dark spots, and fights free radicals
Clindamycin phosphate: An antibiotic that fights acne-contributing bacteria and soothes inflammation
Zinc pyrithione: An antimicrobial that helps keep bacteria and fungi in check while soothing inflammation
Tranexamic acid: A brightening amino acid derivative that helps visibly lighten dark spots and reduce redness
Metronidazole: An antibiotic that can help soothe inflammation, including redness and swelling
Ivermectin: A topical antimicrobial that can help treat rosacea and reduce its symptoms, like redness, inflammation, and acne-like bumps
Inactive ingredients: Aloe Barbadensis Leaf Juice, C13-C14 Isoparaffin, Caprylic/Capric Triglyceride, Deionized Water, Laureth-7, Phenoxyethanol, Polyacrylamide, Tocopheryl Acetate, Triethylene Glycol All formulas containing tretinoin also contain the antioxidant butylated hydroxytoluene (BHT). Formulas containing both niacinamide and azelaic acid, as well as formulas with spironolactone, may also contain propylene glycol.
In the AM: Apply a thin layer of DayPrimeᴿˣ to clean, dry skin and allow it to dry fully before adding sunscreen or makeup. Your personalized prescription will go to work targeting your long-term goals while keeping your skin smooth and ready for whatever comes next.
In the PM: Apply a thin layer of Custom Formulaᴿˣ after cleansing and allow to dry fully before moisturizing. Your personalized prescription will go to work while you sleep.
Since these are prescription products, always follow your licensed dermatology provider’s instructions for how to best use them with your unique skin.
Your Curology dermatology provider will prescribe your formulas containing 3 active ingredients based on your skin quiz, photos, and medical history. Your formulas will target your specific skin concerns and can evolve with you over time!
With consistent use, many patients using these types of ingredients notice a difference with their acne within 6-12 weeks—but everyone’s skin is different, so this timeline might vary for you. It’s also important to remember that this is a long-term journey! We’re not just going for progress, but also prevention.
You may be able to use your HSA or FSA pre-tax dollars for this Curology product, plus some of our other acne treatments and sunscreens. Check with your plan’s administrator to confirm eligibility. Restrictions apply.
After your 30-day free trial, you can update your payment method to your HSA or FSA card via your account dashboard. Or you can use a credit or debit card and submit a claim for reimbursement—just download your itemized receipt for your order from your account dashboard.










