Skip to main content
HydroTret Offers: 2 free gifts
HT offers holiday hero - mobile

The year's best deal

Get your FREE* trial of personalized prescription skincare + 2 FREE gifts when you subscribe today. Up to $60.95 value—just pay $5.45 shipping and handling. Offer ends soon!

*First box lasts 30 days. Subject to medical consultation. Only Rx products are personalized. New subscribers only. Restrictions apply.

How it works

Your personalized skincare routine happens in just a few easy steps.

  1. brunette-woman-with-nose-ring@2x
    1

    Tell us about you.

    We’ll ask you questions about you, your skin, and your skin goals with a simple comprehensive skin quiz.

    We’ll ask you questions about you, your skin, and your skin goals with a simple comprehensive skin quiz.

    brunette-woman-with-nose-ring@2x
  2. provider-holding-purple-bottle-desktop@2x
    2

    Get paired with your provider.

    Once you’ve submitted your “skinfo”, you’ll get connected with one of our licensed dermatology providers to help personalize your treatment plan.

    Once you’ve submitted your “skinfo”, you’ll get connected with one of our licensed dermatology providers to help personalize your treatment plan.

    provider-holding-purple-bottle-mobile@2x
  3. HT LP How it Works Desktop
    3

    Get your formula.

    Your provider prescribes one of our personalized formulas based on a variety of factors specific to your skin, then selects up to 3 clinically proven ingredients that work better together to give you more effective results.

    Your provider prescribes one of our personalized formulas based on a variety of factors specific to your skin, then selects up to 3 clinically proven ingredients that work better together to give you more effective results.

    HT How it Works Mobile
  4. Young brunette with straight hair applying formula in bathroom mirror | Desktop
    4

    Start your routine.

    Once your provider has prescribed your formula and created your personalized plan, your products will be shipped directly to your door every 2 months.

    Once your provider has prescribed your formula and created your personalized plan, your products will be shipped directly to your door every 2 months.

    Young brunette with straight hair applying formula in bathroom mirror | Mobile
Subject to consultation. Subscription required

Limited time only: 2 FREE gifts

Enjoy Limited Edition Spot Patches + Micellar Makeup Remover with your free* trial, just pay $5.45 S&H.

*First box lasts 30 days. Subject to medical consultation. Subscription required. New subscribers only. Restrictions apply.
2 free gifts

Clinically proven active ingredients

Your HydroTretRx formula is customized by a licensed dermatology provider with powerhouse prescription ingredients.*

Tr

Tretinoin
tretinoin@2x
Tretinoin is a vitamin A derivative that’s available by prescription only. The gold standard in anti-aging skincare, it’s up to 20x stronger than over-the-counter retinol.*
Proven to tackle
Dark spots
Fine Lines
Breakouts
Texture

Tr

Tretinoin
tretinoin@2x
Tretinoin is a vitamin A derivative that’s available by prescription only. The gold standard in anti-aging skincare, it’s up to 20x stronger than over-the-counter retinol.*
Proven to tackle
Dark spots
Fine Lines
Breakouts
Texture

Help hydrate while you fight early signs of aging*

Mu - Before
Before
Mu - After
After 6 months
Mu - Before
Before
Mu - After
After 6 months
Results may vary

Mu

I am satisfied with my journey.

Vivian - Before
Before
Vivian - After
After 1 year
Vivian - Before
Before
Vivian - After
After 1 year
Results may vary

Vivian

It changed my skin.

Courtney - Before
Before
Courtney - After
After 1 year
Courtney - Before
Before
Courtney - After
After 1 year
Results may vary

Courtney

My skin is nearly perfect thanks to Curology!

Trevor - Before
Before
Trevor - After
After 2 years
Trevor - Before
Before
Trevor - After
After 2 years
Results may vary

Trevor

My skin has gotten much clearer and smoother.

Melissa - Before
Before
Melissa - After
After 4 years
Melissa - Before
Before
Melissa - After
After 4 years
Results may vary

Melissa

I saw results in the first 2 weeks and was hooked from there. Not sure I’ll ever be without my Curology products.

Annie - Before
Before
Annie - After
After 2 years
Annie - Before
Before
Annie - After
After 2 years
Results may vary

Annie

It helps with my acne, and it helps with the dryness that tretinoin typically causes.

Marian - Before
Before
Marian - After
After 1 year
Marian - Before
Before
Marian - After
After 1 year
Results may vary

Marian

It has improved my skin drastically and helped get rid of the painful cysts I used to get.

Emily - Before
Before
Emily - Before
After 8 months
Emily - Before
Before
Emily - After
After 8 months
Results may vary

Emily

Things are starting to clear up!

Audra - Before
Before
Audra - After
After 1 year
Audra - Before
Before
Audra - After
After 1 year
Results may vary

Audra

[I] switched to the HydroTretᴿˣ, and now that has been working great for me!

Sheri - Before
Before
Sheri - After
After 1 year
Sheri - Before
Before
Sheri - After
After 1 year
Results may vary

Sheri

My skin became smoother with a noticeable glow that made my skin look less tired.

*Results may vary. Product and ingredients subject to medical consultation. Subscription required. Restrictions apply.

Curology

Personalized formula
Prescription-strength ingredients like tretinoin
1:1 support from a licensed dermatology provider
Personalized treatment plan for more effective results

Over-the-counter

One-size-fits-all formula
Non-prescription ingredients only
Research products and ingredients on your own
Results based on trial and error

See the personalized prescription difference

Skincare isn’t one-size-fits all, and we don’t treat it that way. Your personalized formula specifically addresses your unique needs, so you can see better results.

Curology

Personalized formula
Prescription-strength ingredients like tretinoin
1:1 support from a licensed dermatology provider
Personalized treatment plan for more effective results

Over-the-counter

One-size-fits-all formula
Non-prescription ingredients only
Research products and ingredients on your own
Results based on trial and error
Hydro+ Module
Build your routine
with Hydro+
Designed to be our most hydrating collection—from eye gel to cleanser—to support your HydroTretᴿˣ formula

FAQs

What ingredients are in HydroTretᴿˣ?

A licensed dermatology provider selects 3 active ingredients at the right strength for your skin.

Potential active ingredients include:

  • Tretinoin

  • Dexpanthenol (aka provitamin B5)

  • Niacinamide

  • Azelaic acid

Inactive ingredients: Aloe Barbadensis Leaf Juice, C13-14 Isoparaffin, Caprylic/Capric Triglyceride, Deionized Water, Laureth-7, Phenoxyethanol, Polyacrylamide, Tocopheryl Acetate, Triethylene Glycol. 

All formulas containing tretinoin also contain the antioxidant butylated hydroxytoluene (BHT), and formulas containing both niacinamide and azelaic acid may also contain propylene glycol. All formulas containing dexpanthenol also contain propylene glycol.

Who is HydroTretᴿˣ for?

HydroTretᴿˣ is designed for dry, sensitive skin. It may be suitable if you want to add tretinoin into your routine but haven’t been able due to concerns around dryness and irritation. Curology also offers a tretinoin-free HydroTretᴿˣ if that is a better option for your unique skin.

How do you use HydroTretᴿˣ?

Our licensed dermatology providers generally advise that after cleansing with Hydro+ Foaming Gel Cleanser, apply a thin layer of HydroTretᴿˣ to your entire face and neck before bed. Leave on overnight. As always, follow your provider’s instructions for your unique skin.

How is HydroTretᴿˣ personalized?

Your Curology dermatology provider can prescribe you a formula containing up to 3 active ingredients, based on your skin quiz, photos, and consultation. Your formula will target your specific skin concerns and can evolve with you over time!

Get StartedShop ProductsWhy CurologyGuidesOur StoryCommunity
All Rights Reserved 2014-2025 Curology Inc.
Terms of ServicePrivacy Notice
Do Not Sell or Share My Personal Information
1Results may vary. Product and ingredients subject to medical consultation. Subscription required. Restrictions apply. See website for full details and important safety information.