

Renew and hydrate with HydroTretRx
Get a vibrant, healthy-looking glow with a custom, hydrating tretinoin formula.*

Clinically proven active ingredients
Clinically proven active ingredients
Your HydroTretRx formula is customized by a licensed dermatology provider with powerhouse prescription ingredients.*
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Curology
Over-the-counter
See the personalized prescription difference
See the personalized prescription difference
Skincare isn’t one-size-fits all, and we don’t treat it that way. Your personalized formula specifically addresses your unique needs, so you can see better results.
Curology
Over-the-counter
How it works
Your personalized skincare routine happens in just a few easy steps.
- 1
Tell us about you.
We’ll ask you questions about you, your skin, and your skin goals with a simple comprehensive skin quiz.
We’ll ask you questions about you, your skin, and your skin goals with a simple comprehensive skin quiz.
- 2
Get paired with your provider.
Once you’ve submitted your “skinfo”, you’ll get connected with one of our licensed dermatology providers to help personalize your treatment plan.
Once you’ve submitted your “skinfo”, you’ll get connected with one of our licensed dermatology providers to help personalize your treatment plan.
- 3
Get your formula.
Your provider prescribes one of our personalized formulas based on a variety of factors specific to your skin, then selects up to 3 clinically proven ingredients that work better together to give you more effective results.
Your provider prescribes one of our personalized formulas based on a variety of factors specific to your skin, then selects up to 3 clinically proven ingredients that work better together to give you more effective results.
- 4
Start your routine.
Once your provider has prescribed your formula and created your personalized plan, your products will be shipped directly to your door every 2 months.
Once your provider has prescribed your formula and created your personalized plan, your products will be shipped directly to your door every 2 months.

FAQs
What ingredients are in HydroTretᴿˣ?
A licensed dermatology provider selects the active ingredients in your HydroTretRx, but your formula can include:
Tretinoin
Dexpanthenol (aka provitamin B5)
Niacinamide
Azelaic acid
Product and ingredients are subject to consultation.
Who is HydroTretᴿˣ for?
HydroTretᴿˣ is designed for dry, sensitive skin. It may be suitable if you want to add tretinoin into your routine but haven’t been able due to concerns around dryness and irritation. Curology also offers a tretinoin-free HydroTretᴿˣ if that is a better option for your unique skin.
How do you use HydroTretᴿˣ?
Our licensed dermatology providers generally advise that after cleansing with Hydro+ Foaming Gel Cleanser, apply a thin layer of HydroTretᴿˣ to your entire face and neck before bed. Leave on overnight. As always, follow your provider’s instructions for your unique skin.
How is HydroTretRx personalized?
Your Curology dermatology provider can prescribe you a formula containing up to 3 active ingredients, based on your skin quiz, photos, and consultation. Your formula will target your specific skin concerns and can evolve with you over time!